| DB ID | MyCo_5619 |
| Title | The Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection |
| Year | 2020 |
| PMID | 32084267 |
| Fungal Diseases involved | Fungal keratitis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | Patients consented to the management of samples, and the experiment was approved by the Institutional Research Ethics Committee at the Affiliated Hospital of Qingdao University. |
| Site of Infection | Eye |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Corneal samples |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | HMGB1 |
| Biomarker Full Name | HMGB1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | China |
| Cohort | A total of 20 cornea samples of patients with FK (Fusarium 9,Aspergillusinfection 11; aged 40–70 years) and remaining tissues of 20 healthy donors used for keratoplasty were collected as control groups. |
| Cohort No. | 20 |
| Age Group | 40-70 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Western Blot Analysis, qRT-PCR |
| Up Regulation Down Regulation | Up regulated |
| Sequence Data | GenBank No. NM-000071.6 |
| External Link | None |
