MycoBiomDB – Record Details (MyCo_5300)

Biomarker Record Details

Database ID: MyCo_5300
DB IDMyCo_5300
TitleMannitol and inflammatory markers in the cerebral spinal fluid of HIV-infected patients with cryptococcal meningitis
Year2008
PMID18266014
Fungal Diseases involvedCryptococcal meningitis
DiseaseCryptococcosis (Cryptococcus Infection)
Associated Medical ConditionHIV-AIDS
GenusCryptococcus
Speciesneoformans
OrganismCryptococcus neoformans
Ethical StatementThis study was approved by the Institutional Review Boards at both. The George Washington University Medical Center and the Veterans Affairs Medical Center in Washington, DC, and the Research and Development Committee of the Veterans Affairs Medical Center i Washington, DC.
Site of InfectionUnspecified
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceCerebrospinal fluid (CSF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTNF-α
Biomarker Full NameTumor Necrosis Factor alpha
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortNone
Cohort No.None
Age GroupNone
P Valuep<0.001
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueImmunofluorescence
TechniqueImmunoassay
Analysis MethodMultiplex cytokine bead array system analysis
ELISA kitsmultiplex cytokine bead array system (Bio-Plex kits; Bio-Rad, Hercules, CA).
Assay DataNone
Validation Techniques usedGas Chromatography/Mass Spectroscopy (GC/MS) Analysis, Multiplex cytokine bead array system analysis
Up Regulation Down RegulationIncrease
Sequence DataNone