MycoBiomDB – Record Details (MyCo_5259)

Biomarker Record Details

Database ID: MyCo_5259
DB IDMyCo_5259
TitleSoluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum
Year2014
PMID24483326
Fungal Diseases involvedFungal infection
Associated Medical ConditionNone
GenusVerticillium
Specieslongisporum
OrganismVerticillium longisporum
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typePlant extracts
Sample sourceExtracted RNA
Host GroupPlant
Host Common nameArabidopsis thaliana
Host Scientific nameArabidopsis thaliana
Biomarker NameUGT72E3
Biomarker Full NameUDP-glycosyl transferase 72E3
Biomarker TypeDiagnostic
BiomoleculemRNA
Geographical LocationGermany
CohortPlant lines used were wild-type Arabidopsis thaliana (L.) Heynh ecotype Columbia 0 (Col 0), fah1-2 (Chapple et al., 1992), ref1-s (SALK_27911), sng1-1 (Lorenzen et al., 1996), C4H:F5H (Meyer et al., 1996), UGT72E1-OE, UGT72E2-OE and UGT73E1-OE (Lanot et al., 2006, 2008). The V. longisporum isolate Vl43 (Zeise & von Tiedemann, 2002) was obtained from A. von Tiedemann (Georg-August-University, G€ ottingen).
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismVerticillium longisporum is a soil-borne fungus which causes vascular disease primarily in Brassicaceae. Triggered by plant root exudates, fungal hyphae develop from microsclerotia, penetrate the root epidermis, grow through the root cortex and enter the xylem elements from where V. longisporum spreads throughout the plant. The life cycle is completed after formation of microsclerotia on senescent tissue.
TechniqueAnalytic
Analysis MethodUPLC-TOF-MS
ELISA kitsNone
Assay DataNone
Validation Techniques usedUPLC-TOF-MS, qRT-PCR
Up Regulation Down RegulationInduced
Sequence DataNone
External LinkNone