MycoBiomDB – Record Details (MyCo_5035)

Biomarker Record Details

Database ID: MyCo_5035
DB IDMyCo_5035
TitleNon-invasive and invasive diagnoses of aspergillosis in a rat model by mass spectrometry
Year2017
PMID29184111
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementAll animal experiments were conducted in accordance with the regulations and guidelines of the Czech Animal Protection Act (No. 246/1992) with the approval of the Czech Ministry of Education, Youth and Sports (MSMT- 21235/2013-12) and the institutional Animal Welfare Committee of the Faculty of Medicine and Dentistry o Palacky University in Olomouc, Czech Republic.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceUrine
Host GroupAnimal
Host Common nameRat
Host Scientific nameRattus norvegicus
Biomarker NameTriacetylfusarinine C
Biomarker Full NameTriacetylfusarinine C
Biomarker TypeDiagnostic
BiomoleculeSiderophore
Geographical LocationCzech Republic
CohortThe studies were performed using two groups of female Lewis rats (2–3 months old, Harlan Laboratories).
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodMALDI-FTICR Mass spectrometry
ELISA kitsNone
Assay DataNone
Validation Techniques usedMALDI-FTICR Mass spectrometry
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone