MycoBiomDB – Record Details (MyCo_4635)

Biomarker Record Details

Database ID: MyCo_4635
DB IDMyCo_4635
TitleProteomic profiling of exosomes in a mouse model of Candida albicans endophthalmitis
Year2022
PMID35618014
Fungal Diseases involvedCandida albicans endophthalmitis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementMice were treated in compliance with the Association for Research in Vision and Ophthalmology (ARVO) Statement for the Use of Animals in Ophthalmic and Vision Research, and all procedures were approved by the Institutional Animal Ethics Committee (IAEC)-SLL/PCT/IAEC/ 20–21/A.
Site of InfectionEye
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted Eye Tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameAQP5
Biomarker Full NameAquaporin 5
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationIndia
Cohort6–8 weeks old C57BL/6 mice (both male and female mice) were acquired and housed at the Sipra Labs (Hyderabad, India).
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueLiquid chromatography
Analysis MethodLC-MS/MS Based Proteomics Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedWestern blot Analysis, ELISA, LC-MS/MS Based Proteomics Analysis
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone