| DB ID | MyCo_4428 |
| Title | Use of intravoxel incoherent motion diffusion-weighted MR imaging for assessment of treatment response to invasive fungal infection in the lung |
| Year | 2016 |
| PMID | 27180185 |
| Fungal Diseases involved | Invasive fungal infection |
| Associated Medical Condition | None |
| Genus | None |
| Species | None |
| Organism | None |
| Ethical Statement | The prospective study was approved by our institutional review board and written informed consent was obtained from all participants. |
| Site of Infection | Lungs |
| Opportunistic invasive | None |
| Sample type | None |
| Sample source | None |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IVIM-ADC |
| Biomarker Full Name | Intravoxel incoherent motion derived parameters and apparent diffusion coefficient |
| Biomarker Type | Predictive |
| Biomolecule | None |
| Geographical Location | China |
| Cohort | Forty-six consecutive patients (mean age, 33.9 ± 13.0 y) with newly diagnosed invasive fungal infection (IFI) in the lung according to EORTC/MSG criteria wer prospec-tively enrolled. |
| Cohort No. | 46 |
| Age Group | 33.9 ±13 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive fungal infection (IFI) has emerged as an important cause of life-threatening opportunistic respiratory complication in severely immunocompromised patients. Acute IFI is a rapidly progressive infection, with an associated mortality rate of up to 64 %. Without adequate therapy, IFI will almost always progress to relentless fatal pneumonia. It may be further complicated by dissemination to the central nervous system or by extension to contiguous intrathoracic structures, including the great vessels and the heart. |
| Technique | Analytic |
| Analysis Method | IVIM-MRI Imaging analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | IVIM-MRI Imaging analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
