MycoBiomDB – Record Details (MyCo_4421)

Biomarker Record Details

Database ID: MyCo_4421
DB IDMyCo_4421
TitleDisseminated Cryptococcosis Due to Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in the Absence of Pulmonary Alveolar Proteinosis
Year2017
PMID28013480
Fungal Diseases involvedCryptococcosis
Associated Medical ConditionNone
GenusCryptococcus
Speciesspp.
OrganismCryptococcus spp.
Ethical StatementThis study was performed with the approval of the Ethics Committees of Chang Gung University and China Medical University.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameSTAT5
Biomarker Full NameSTAT5
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationTaiwan
CohortEleven patients with cryptococcal infection were screened for anti-GM-CSF autoantibodies. The diagnosis of cryptococco-sis was based on culture of blood, cerebrospinal fluid, or tis-sue.
Cohort No.11
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodIntracellular Staining
ELISA kitsHuman MIP-1α ELISA Kit (eBioscience)
Assay DataNone
Validation Techniques usedELISA, Intracellular Staining
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone