MycoBiomDB – Record Details (MyCo_4393)

Biomarker Record Details

Database ID: MyCo_4393
DB IDMyCo_4393
TitleComparison of lateral flow technology and galactomannan and (1->3)-beta-D-glucan assays for detection of invasive pulmonary aspergillosis
Year2009
PMID19793899
Fungal Diseases involvedInvasive pulmonary aspergillosis
DiseaseAspergillosis (Aspergillus Infection)
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionUnspecified
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupAnimal
Host Common namePig
Host Scientific nameCavia porcellus
Biomarker NameLFD test
Biomarker Full NameLateral Flow device test
Biomarker TypeDiagnostic
BiomoleculeNA
Geographical LocationUSA
CohortImmunosuppressed male Hartley guinea pigs (Charles River Laboratories) were exposed to conidia for 1 h in an aerosol chamber.
Cohort No.None
Age GroupNone
P ValueNone
Sensitivity1
Specificity1
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueLateral flow
TechniqueImmunoassay
Analysis MethodLateral Flow device analysis
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Marnes la Coquette, France)
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay, FDA Approved -Platelia Aspergillus Ag ELISA, Lateral Flow device analysis
Up Regulation Down RegulationPositive
Sequence DataNone