MycoBiomDB – Record Details (MyCo_4319)

Biomarker Record Details

Database ID: MyCo_4319
DB IDMyCo_4319
TitleImmunoproteomics based identification of thioredoxin reductase GliT and novel Aspergillus fumigatus antigens for serologic diagnosis of invasive aspergillosis
Year2012
PMID22251604
Fungal Diseases involvedInvasive aspergillosis
DiseaseAspergillosis (Aspergillus Infection)
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementThe study protocol was approved by the Ethics Committee of the hospital and informed consent was obtained from all patients included in the study
Site of InfectionUnspecified
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameFumarylacetoacetate hydrolase FahA
Biomarker Full NameFumarylacetoacetate hydrolase FahA
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationChina
CohortSix patients with proven IA, and different underlying dis- eases and expressing high levels of anti-Aspergillus antibo-dies were selected for the immunoproteomic analysis.
Cohort No.6
Age Group30-65
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueProteomics
TechniqueComputational
Analysis MethodImmunoproteomics Approach
ELISA kitsNone
Assay DataNone
Validation Techniques usedImmunoproteomics Approach
Up Regulation Down RegulationPositive
Sequence DataGenBank Accession No: GI:70989411