MycoBiomDB – Record Details (MyCo_3912)

Biomarker Record Details

Database ID: MyCo_3912
DB IDMyCo_3912
TitleMast cell tryptase changes with Aspergillus fumigatus - Host crosstalk in cystic fibrosis patients
Year2018
PMID29456195
Fungal Diseases involvedAspergillosis
Associated Medical ConditionCystic fibrosis
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementUnder the French law, ethics committee approval and patient consent were not required for this type of non-interventional study, provided the patients had received information and retained the right to oppose the use of excess serum and anonymized medical data
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTryptase
Biomarker Full NameTryptase
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationFrance
CohortSeventy-six CF patients were studied.
Cohort No.76
Age Group2–59
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodImmunoCAP assay
ELISA kitsNone
Assay DataImmunoCAP (ThermoFisher Scientific, Uppsala, Sweden)
Validation Techniques usedImmunoCAP assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone