MycoBiomDB – Record Details (MyCo_3889)

Biomarker Record Details

Database ID: MyCo_3889
DB IDMyCo_3889
TitlePathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans
Year2008
PMID18249133
Fungal Diseases involvedCandida sepsis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBody fluid
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameIL-8
Biomarker Full NameInterleukin-8
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortIn this study, 325 posttraumatic patients with sepsis and septic shock were collected over a period of 4 years. Over a ten-month period, 47 of these 325 patients were monitored daily during their treatment in the anesthesiological intensive care unit (ICU) of the University Hospital Ulm, Germany.
Cohort No.47
Age Group57.3 ± 10.4
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodHuman cytokine Lincoplex assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedPyrosequencing Analysis, Human cytokine Lincoplex assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone