| DB ID | MyCo_3712 |
| Title | What's new in invasive pulmonary aspergillosis in the critically ill |
| Year | 2014 |
| PMID | 24647810 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Disease | Aspergillosis (Aspergillus Infection) |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | None |
| Site of Infection | Unspecified |
| Opportunistic invasive | Invasive/Opportunistic |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GM |
| Biomarker Full Name | Galactomannan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Multi-Location |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive pulmonary aspergillosis (IPA) has been increasingly recognized as an emerging and understudied opportunistic infection in critically ill patients without classic host factors reflecting profound immunosuppres- sion as defined by the European Organization for the Research and Treatment of Cancer/Mycosis Study Group (EORTC/MSG). Impaired immune response fol- lowing critical illness and particular underlying conditions put patients at risk of IPA. Predisposing conditions frequently met in intensive care units (ICUs) include chronic obstructive pulmonary disease (COPD), corticosteroid (CS) use, decompensated liver disease, acute respiratory distress syndrome (ARDS), severe sep-sis, post-sepsis immunoparalysis, and H1N1 virus infection (especially if CS prior to ICU admission). |
| Sub Technique | Lateral flow |
| Technique | Immunoassay |
| Analysis Method | GM Assay |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | GM Assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
