| DB ID | MyCo_3506 |
| Title | Fractional exhaled nitric oxide, a potential biomarker for evaluating glucocorticoids treatment and prognosis in allergic bronchopulmonary aspergillosis |
| Year | 2024 |
| PMID | 38777120 |
| Fungal Diseases involved | Allergic bronchopulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | The study was approved by the ethics committee of Shanghai Pulmonary Hospital (numbers K18-153 and K17-134). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | None |
| Sample source | Exhaled air |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | FeNO |
| Biomarker Full Name | Fractional exhaled nitric oxide |
| Biomarker Type | Prognostic |
| Biomolecule | Volatile |
| Geographical Location | China |
| Cohort | 58 patients were enrolled in the retrospective study. |
| Cohort No. | 58 |
| Age Group | 54.6±16.5 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Allergic bronchopulmonary aspergillosis (ABPA) is a complex pul- monary allergic disease characterized by poor asthma control, hemoptysis, and mucous blockage in lung images. Immunologic reactions mediated against Aspergillus fumigatus are believed to be the main cause. The global burden of ABPA potentially reached 5 mil- lion people, which is more than previously expected. The clinical heterogeneity associated with ABPA poses challenges in providing timely treatment during the early stages of the disease, potentially leading to complications such as bronchiectasis and pulmonarybrosis. |
| Technique | Analytic |
| Analysis Method | Fractional exhaled nitric oxide analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Fractional exhaled nitric oxide analysis |
| Up Regulation Down Regulation | Increase/Decrease |
| Sequence Data | None |
| External Link | None |
