MycoBiomDB – Record Details (MyCo_3339)

Biomarker Record Details

Database ID: MyCo_3339
DB IDMyCo_3339
TitleThe GITRL-GITR system alters TLR-4 expression on DC during fungal infection
Year2009
PMID19272591
Fungal Diseases involvedFungal infection
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementProtocols were approved by the Animal Study Committees of the University of Perugia according to governmen-tal guidelines for animal care.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted Tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameGITR
Biomarker Full NameGlucocorticoid-induced TNFR-related
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationItaly
CohortSv129 GITR-deficient (GITR / ) mice were generated by homol-ogous recombination. Mice were maintained under specific-pathogen-free conditions in the Animal Care Facility of the University of Perugia.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodFlow Cytometry Analysis
ELISA kitsELISA kits (BD Biosciences Pharmingen).
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis, qRT-PCR, ELISA, Western blotting
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone