| DB ID | MyCo_3231 |
| Title | Challenging diagnosis of chronic cerebral fungal infection: Value of (1→3)-ß-D-glucan and mannan antigen testing in cerebrospinal fluid and of cerebral ventricle puncture |
| Year | 2020 |
| PMID | 32470986 |
| Fungal Diseases involved | Chronic cerebral Fungal infection |
| Associated Medical Condition | None |
| Genus | Cladophialophora |
| Species | bantiana |
| Organism | Cladophialophora bantiana |
| Ethical Statement | The human samples were stored in Tours University Hospital collectionDC-2008 308,approvedon22/01/2016bytheFrench Ministry of Higher Education and Research. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Cerebrospinal fluid (CSF) |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | France |
| Cohort | Three patients (patients 1 to 3) with confirmed chronic CNS fungal infection diagnosis were included. Sixteen controls (con- trols 1 to 16) suffering from miscellaneous nonfungal CNS dis- eases were enrolled: nine cases of infectious disease, five cases of blood malignancies with neurological involvement, one was of vasculitis, and one case of metabolic syndrome. All the pa- tients were admitted to Tours University Hospital in Tours,France. |
| Cohort No. | 3 |
| Age Group | 39-58 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | FDA Approved-Fungitell assay |
| ELISA kits | Platelia Candida Ag Plus® kit (BioRad, Marnes-la- Coquette,France) |
| Assay Data | FDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA |
| Validation Techniques used | FDA Approved-Fungitell assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
