MycoBiomDB – Record Details (MyCo_3215)

Biomarker Record Details

Database ID: MyCo_3215
DB IDMyCo_3215
TitleA prospective study of fungal biomarkers to improve management of invasive fungal diseases in a mixed specialty critical care unit
Year2017
PMID28384600
Fungal Diseases involvedInvasive fungal infection
DiseasePneumocystis
Associated Medical ConditionNone
GenusPneumocystis
Speciesjirovecii
OrganismPneumocystis jirovecii
Ethical StatementPrior approval for this study was obtained from the St. James’s Hos- pital Research Ethics Committee (Reference 2012/39/01).
Site of InfectionUnspecified
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationIreland
CohortA total of 100 patients were recruited in the study.
Cohort No.100
Age Group20–85
P Valuep<0.0001
Sensitivity0.63
Specificity0.83
Positive Predictive Value0.65
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueChemiluminescence
TechniqueImmunoassay
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay
Up Regulation Down RegulationIncrease
Sequence DataNone