| DB ID | MyCo_3110 |
| Title | Can bacteraemia lead to false positive results in 1,3-beta-D-glucan test? Analysis of 83 bacteraemia episodes in high-risk patients for invasive fungal infections |
| Year | 2012 |
| PMID | 21907303 |
| Fungal Diseases involved | Invasive fungal infection |
| Associated Medical Condition | Bacteraemia |
| Genus | None |
| Species | None |
| Organism | None |
| Ethical Statement | This study was conducted at the Erciyes University Hospital, a 1300-bed tertiary care centre in Kayseri, Turkey. The study was approved by the ethics board of the Medical Faculty. The records of the Infection Control Committee were reviewed to identify the patients with bacteraemia who were hospitalized in the haematology ward and stem cell transplantation unit. All medical records, laboratory data, and discharge summaries were evaluated to identify the cases. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Turkey |
| Cohort | Patients who had undergone the BDG test at least once within 5 days of a positive blood culture were included in the study. BDG levels in the sera were assayed using the Fungitell kit (Associates of Cape Cod, East Falmouth, MA) according to the manufacturer’s specifications. Eighty-three bacteraemic episodes were identified in 71 patients. BDG positivity was detected in 14 patients with bacteraemia. |
| Cohort No. | 71 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | FDA approved Fungitell assay |
| ELISA kits | None |
| Assay Data | FDA approved Fungitell assay |
| Validation Techniques used | FDA approved Fungitell assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
