MycoBiomDB – Record Details (MyCo_3103)

Biomarker Record Details

Database ID: MyCo_3103
DB IDMyCo_3103
TitleAssessment of serum (1->3)-beta-D-glucan concentration as a measure of disease burden in a murine model of invasive pulmonary aspergillosis
Year2007
PMID18160526
Fungal Diseases involvedInvasive pulmonary aspergillosis
DiseaseAspergillosis (Aspergillus Infection)
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementNone
Site of InfectionUnspecified
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortTo achieve these objectives, outbred ICR mice (Harlan), weighing between 18 and 22 g, were used in the study
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueChemiluminescence
TechniqueImmunoassay
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay
Up Regulation Down RegulationPositive
Sequence DataNone