MycoBiomDB – Record Details (MyCo_3021)

Biomarker Record Details

Database ID: MyCo_3021
DB IDMyCo_3021
TitleThe current management landscape: aspergillosis
Year2016
PMID27880666
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSweden
CohortNone
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismInvasive aspergillosis (IA), usually affecting the respiratory tract, occurs almost exclusively in patients with varying degrees of immunodeficiency, and produces a wide range of clinical manifes- tations. The nature and extent of the compromised immunity, as well as the prophylactic use of antifungals and accommodation in protective environments, predict the risk. Patients at high risk include allogeneic stem cell transplant recipients, those being treated for acute myeloid leukaemia, myelodysplastic syndromes or aplastic anaemia, and subgroups of solid organ transplant recipients.
TechniqueELISA
Analysis MethodFDA approved Fungitell assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedELISA Based, Aspergillus PCR, FDA approved Fungitell assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone