MycoBiomDB – Record Details (MyCo_2969)

Biomarker Record Details

Database ID: MyCo_2969
DB IDMyCo_2969
TitleConcurrent lung infections in patients with hematological malignancies and invasive pulmonary aspergillosis: how firm is the Aspergillus diagnosis?
Year2012
PMID22580034
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionHematological malignancies
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThe study protocol was approved by The MD Anderson Cancer Center Board and written informed consent was obtained from every patient.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortHere found 126 such patients that frequently had coinfections (49%) with respiratory pathogens other than Aspergillus species, with a higher rate in patients with probable IPA (53%) than in those with proven IPA
Cohort No.126
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved -Platelia Aspergillus ELISA
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus; Bio-Rad Laboratories, Hercules, CA)
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone