MycoBiomDB – Record Details (MyCo_2908)

Biomarker Record Details

Database ID: MyCo_2908
DB IDMyCo_2908
TitleProspective evaluation of clinical and biological markers to predict the outcome of invasive pulmonary aspergillosis in hematological patients
Year2011
PMID22170907
Fungal Diseases involvedInvasive pulmonary aspergillosis
DiseaseAspergillosis (Aspergillus Infection)
Associated Medical ConditionHematological Patients
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThe protocol was approved by the ethics committee of the Saint Louis teaching hospital in Paris, France.
Site of InfectionUnspecified
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationFrance
CohortA total of 57 patients (4 with proven, 44 with probable, and 9 with possible aspergillosis according to the revised EORTC/MSG [European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and National Institute of Allergy and Infectious Diseases Mycoses Study Group] definitions) were included.
Cohort No.57
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueELISA
TechniqueImmunoassay
Analysis MethodFDA Approved -Platelia Aspergillus Ag ELISA
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Marnes la Coquette, France)
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus Ag ELISA
Up Regulation Down RegulationIncrease
Sequence DataNone