MycoBiomDB – Record Details (MyCo_2642)

Biomarker Record Details

Database ID: MyCo_2642
DB IDMyCo_2642
TitleEfficacy of dupilumab and biomarkers for systemic corticosteroid naïve allergic bronchopulmonary mycosis
Year2020
PMID32917523
Fungal Diseases involvedAllergic bronchopulmonary aspergillosis
Associated Medical ConditionNone
GenusPenicillium
Speciesspp.
OrganismPenicillium spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameCCL2
Biomarker Full NameCCL2
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortA 72-year-old Japanese woman who had cataract and treatment history of non-tuberculosis mycobacterium (NTM) had been treated with inhaled corticosteroid, long acting b2 adrenergic agonist, long acting muscarinic antagonist and leukotriene receptor agonist for asthma diagnosed 5 years ago and experienced asthma exacerbations for twice in previous year. She had no history of sinusitis, smoking, dust exposure, or treatment with anti-fungal agents was included in the study.
Cohort No.1
Age Group72
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsmultiplex ELISA Kit (Eve Technologies, Calgary, Alberta, Canada) and (for periostin, Shino-test, Tokyo, Japan).
Assay DataNone
Validation Techniques usedmultiplex ELISA assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone