MycoBiomDB – Record Details (MyCo_2393)

Biomarker Record Details

Database ID: MyCo_2393
DB IDMyCo_2393
TitleGalactomannan detection as a tool for the diagnosis and management of cardiac aspergillosis in 2 immunocompetent patients
Year2008
PMID18945209
Fungal Diseases involvedCardiac aspergillosis
DiseaseAspergillosis (Aspergillus Infection)
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionUnspecified
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSpain
CohortSerum galactomannan antigen detection was used for the diagnosis and follow-up of cardiac aspergillosis after surgery in 2 nonneutropenic patients. The first patient was a 13-year-old nonneutropenic boy with congenital heart disease that included transposition of the great arteries, ventricular septal defect, and pulmonary stenosis. The second patient was a 12-year-old nonneutropenic boy with pulmonary valve atresia and ventricular septal defect. Sur- gery was performed at 3 years of age (ventricular septal defect closure and right ventricle–pulmonary artery conduit).
Cohort No.2
Age GroupDec-13
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
Sub TechniqueELISA
TechniqueImmunoassay
Analysis MethodELISA Based
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Marnes la Coquette, France)
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus Ag ELISA
Up Regulation Down RegulationPositive
Sequence DataNone