| DB ID | MyCo_2366 |
| Title | Evaluation of some immunological markers in co-infection of COVID-19 with thrush candidiasis |
| Year | 2024 |
| PMID | 38747876 |
| Fungal Diseases involved | Thrush candidiasis |
| Associated Medical Condition | COVID-19 |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | This study was approved by the ethical committee of the Faculty of Medicine, University of AL-Qadisiyah, and informed consent was obtained from all individuals, and permission was obtained from the Al-Diwaniaya Teaching Hospital/Quarantine unit. |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-10 |
| Biomarker Full Name | Interleukin-10 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Iraq |
| Cohort | The study involved 70 patients (30 patients with COVID-19, 17 patients with thrush candidiasis, and 23 patients with Thrush Candida albicans) and 50 healthy individuals as a control group. COVID-19 was identified using RT-PCR, while C. albicans were identified through culture media, biochemical testing, and oral swabs. |
| Cohort No. | 70 Patients + 50 Healthy Control |
| Age Group | 4–80 years |
| P Value | p=0.093 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Thrush candidiasis, caused by Candida albicans, is a severe parasitic disease causing clinical issues and COVID- 19-related complications. The exact pathophysiology of candidiasis in COVID-19 patients is not fully understood, and there is limited information on contagious co-contaminations. Deficient understanding and lack of preventive measures may lead to misdiagnosis and potentially destroy COVID-19 outcomes. The meaning of the sole impacts of the safe reaction on parasitic contaminations needs further examination. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Decrease |
| Sequence Data | None |
| External Link | None |
