| DB ID | MyCo_1974 |
| Title | X-linked immunodeficient (XID) mice exhibit high susceptibility to Cryptococcus gattii infection |
| Year | 2021 |
| PMID | 34526536 |
| Fungal Diseases involved | Cryptococcosis |
| Disease | Cryptococcosis (Cryptococcus Infection) |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | gattii |
| Organism | Cryptococcus gattii |
| Ethical Statement | None |
| Site of Infection | Unspecified |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | B-1 cell |
| Biomarker Full Name | B-1 cell |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Brazil |
| Cohort | Isogenic female mice of BALB/c-XID lineage and BALB/c controls, female, aged 8 to 12 weeks, weigh- ing an average of 20.5 and 24.5 g, respectively were used in this study. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Cryptococcosis is an infectious disease caused by the fungal species Cryptococcus neoformans and Cryptococcus gattii. Both are globally distributed, although C. gattii is generally seen as a tropical or subtropical ¬ fungus. Cryptococcosis affects mostly \ immunocompromised individuals causing severe lung disease and meningoen- cephalitis, with C. gattii being able to infect immunocompetent ¬ hosts. |
| Sub Technique | ELISA |
| Technique | Immunoassay |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
