| DB ID | MyCo_1926 |
| Title | Evaluation of procalcitonin as a diagnostic marker in neonatal sepsis |
| Year | 2018 |
| PMID | 29567889 |
| Fungal Diseases involved | Neonatal sepsis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | This study was submitted at the institutional human ethics committee and approval was obtained. Informed consent was obtained from both parents for all the neonates who were involved in the study. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | PCT |
| Biomarker Full Name | Procalcitonin |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | India |
| Cohort | A prospective cross sectional study was conducted at our tertiary care hospital in Puducherry. The study was conducted over a period of 5 months from November 2015 to 2016. The study included all neonates with clinical signs of sepsis. A total of 75 neonates were included in our study. |
| Cohort No. | 75 |
| Age Group | None |
| P Value | None |
| Sensitivity | 0.889 |
| Specificity | 0.803 |
| Positive Predictive Value | 0.5501 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Neonatal sepsis is an early infection occurring within 28 days of the postnatal life. Neonatal sepsis is divided into two types as early onset sepsis which occurs within 3 days of birth and late onset sepsis which occurs later. It inflicts an increase in morbidity and mortality among neonates. The estimated global neonatal death rates indicate 40% mortality due to sepsis. Further lack of accurate assessment and limited medical resources hamper accurate detection of neonatal sepsis among the developing countries. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
