MycoBiomDB – Record Details (MyCo_1723)

Biomarker Record Details

Database ID: MyCo_1723
DB IDMyCo_1723
TitleModulation of the systemic inflammatory response by recombinant human interleukin-11: a prospective randomized placebo controlled clinical study in patients with hematological malignancy
Year2006
PMID16644288
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionHematological malignancy
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamerhIL-11
Biomarker Full NameRecombinant human interleukin-11
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUAE
CohortPersons with a diagnosis of acute myeloid or lymphoblastic leukemia or non-Hodgkin’s lymphoma were admitted to the Haematology Ward of Tawam Hospital. A total of 898 daily serum samples (466 placebo group, 432 rhIL-11 group) were collected for cytokine analysis, representing a mean observation period of 24 days on placebo treatment and 21.5 days on rhIL-11 treatment.
Cohort No.898
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitshuman ELISA kits: sTNFRI DuoSet ELISA kit [Cat #DY225] from R&D systems (Minneapolis, MN, USA)
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone