| DB ID | MyCo_1579 |
| Title | False positive galactomannan Platelia due to piperacillin-tazobactam |
| Year | 2011 |
| PMID | 22153703 |
| Fungal Diseases involved | Invasive aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GM |
| Biomarker Full Name | Galactomann |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | France |
| Cohort | A retrospective analysis was made on patients at risk hospitalized in the hematology and oncology ward between January 2009 and the end of December 2010. We noted that 207 patients were included (n = 207), accounting for 69 false positive and 138 true negative results. |
| Cohort No. | 207 |
| Age Group | None |
| P Value | None |
| Sensitivity | 1 |
| Specificity | 0.68 |
| Positive Predictive Value | 0.16 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive aspergillosis (IA) is due to a filamentous fungus, Aspergillus sp., and 84% to Aspergillus fumigatus in France. The death rate at 3 months is still high 30 to 40% of treated patients. It especially affects patients presenting with aplastic anemia in the hematology and oncology ward. The diagnosis of IA is difficult to make because symptoms lack specificity. It is made on several criteria: host factors, clinical and mycological criteria, according to EORTC criteria reviewed in 2008. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | GM Elisa Platelia (Bio Rad®) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
