| DB ID | MyCo_1457 |
| Title | Does leukotriene F4 play a major role in the infection mechanism of Candida sp.? |
| Year | 2020 |
| PMID | 32707317 |
| Fungal Diseases involved | Candidemia |
| Disease | Candidiasis (Candida Infection) |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | The research was conducted according to the guidelines provided in the Declaration of Helsinki. The Local Ethics Committee approved this study (CEP no. 003/2011), and all patients or their guardians signed the provided informed consent forms. |
| Site of Infection | Unspecified |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-1β |
| Biomarker Full Name | Interleukin-1β |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Brazil |
| Cohort | During the study period, critical patients, over 18 years old, with sepsis, taking broad-spectrum antibiotics, and with more than 5 days of critical-care assistance were included. |
| Cohort No. | 36 |
| Age Group | 18-79 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Sub Technique | Flow cytometry |
| Technique | Cell-based Assay |
| Analysis Method | Cytometric Bead Array (CBA) Analysis |
| ELISA kits | Human Enhanced Sensitivity Master Buffer Kit (BD Biosciences, San Jose, CA, USA) |
| Assay Data | FDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA |
| Validation Techniques used | Cytometric Bead Array (CBA) Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
