| DB ID | MyCo_1370 |
| Title | Seasonal variation of serum KL-6 concentrations is greater in patients with hypersensitivity pneumonitis |
| Year | 2014 |
| PMID | 25098177 |
| Fungal Diseases involved | Hypersensitivity pneumonitis |
| Associated Medical Condition | None |
| Genus | Trichosporon |
| Species | asahii |
| Organism | Trichosporon asahii |
| Ethical Statement | The Ethical Review Board of the Kochi Medical School, Kochi University, reviewed the study design and protocol. Approval was waived according to the Ethical Guideline for Clinical Research issued by the Ministry of Health, Labour and Welfare, Japan. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | KL-6 |
| Biomarker Full Name | Krebs von den Lungen-6 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | Electronic medical records of patients with registered diagnoses of ILD who consulted our university hospital from April 1, 2009 to March 31, 2014 were reviewed by two pulmonologists. The final study population consisted of 96 ILD patients classified as IPF (n = 16), NSIP (n = 16), CVD-IP (n = 33), House-HP (n = 9), Bird-HP (n = 9), and combined pulmonary fibrosis and emphysema (CPFE, n = 13), based on diagnostic criteria for each. |
| Cohort No. | 96 |
| Age Group | None |
| P Value | None |
| Sensitivity | 0.889 |
| Specificity | 0.538 |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Immunological assay |
| Analysis Method | Chemiluminescent enzyme immunoassay LUMIPULSE |
| ELISA kits | None |
| Assay Data | chemiluminescent enzyme immunoassay LUMIPULSE KL-6 using a KL-6 antibody (EIDIA Co., Ltd, JPN). |
| Validation Techniques used | Chemiluminescent enzyme immunoassay LUMIPULSE |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
