ExoProPred

Welcome to EIPpred

Understanding the effectiveness of peptides against bacterial pathogens, such as Escherichia coli (E. coli), is crucial for developing novel therapeutic strategies. Predicting the Minimum Inhibitory Concentration (MIC) values of peptides can provide valuable insights into their antibacterial activity of the peptides and aid in drug discovery efforts. Therefore, introducing EIPpred, MIC prediction tool for peptides against E. coli, a rapid and reliable solution leveraging the machine learning algorithms to accurately assess antibacterial activity. With customizable inputs and an intuitive interface, users can input peptide sequences, customize prediction settings, and visualize results seamlessly. Our tool offers accurate and rapid predictions to guide researchers in the development of antibacterial peptides






Cite: To be updated soon

Modules

Predict

This tool allows the user to predict the activity of inhibitory peptides against E. coli in terms of MIC value from their amino acid sequence. The module allows users to make the prediction based on the top 1000 selected features using mRMR technique.

Design

This module facilitates the user to generate the mutants/patterns of the desired residue mutation (single or dipetide residue) and position selected by the user from the submitted sequence(s). It allows the user to design the best mutant with the lowest MIC value.

Protein scan

This module allows the user to scan the sequence(s) in order to recognize the important regions in the protein sequence(s) having the highest inhibitory activity against E.coli as per the lenght selected by the user.

Framework

This module facilitates the user to understand the architecture behind the working and the dataset used by the model.

Team

Meet our dedicated team who contributed in developing this webserver,were all collaborated seamlessly to develop and maintain this platform, ensuring its accuracy, reliability, and user-friendly interface.

Standalone

Standalone page of EIP prediction webserver contains all the scripts and files necessary for the user to run all facilities on their local machines. All the python codes, files, and instructions are also provided in the EIPpred's GitHub repository.

Contact

Contact Image

Dr. Gajendra P. S. Raghava
Professor & Head of the Department (Computational Biology)
Indraprastha Institute of Information Technology, Okhla Phase 3, New Delhi, India

Email: raghava@iiitd.ac.in,
raghavagps@gmail.com,
raghavagps@yahoo.com
Website: http://webs.iiitd.edu.in/raghava/
Phone: +91-26907444
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