Epidermal Growth Factor Receptor Inhibitor Database


General Property
Molceule ID (DB)EGIN0005039
Inhibitor ClassQuinazoline
Molecule Name in Refrence Article9
IUPAC NameN‐(3‐phenylphenyl)‐7H,8H‐[1,4]dioxino[2,3‐g]quinazolin‐4‐amine
FormulaC19H19N3O2
Mass321.3731
Exact Mass321.147726867
Composition C (71.01%), H (5.96%), N (13.08%), O (9.96%)
Atom Count43
PI8.25
Smiles[H]N(C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=N[C@@]2([H])OC([H])([H])C([H])([H])C([H])([H])O[C@@]12[H]
InChI1S/C19H19N3O2/c1-2-6-14(7-3-1)15-8-4-9-16(12-15)22-18-17-19(21-13-20-18)24-11-5-10-23-17/h1-4,6-9,12
-13,17,19H,5,10-11H2,(H,20,21,22)/t17-,19-/m0/s1
InChIKeyLOXBQRLNSKUQTP-HKUYNNGSSA-N
2D Structure
Structure Backbone
View Structure in JmolClick to view 3 d structure                            Download Mol File
Drug Like PropertyDruglikeliness
Symmetry & GeometrySymmetry And Geometrical Information
Activity & Binding Activity against isoform and covalant binding information
Topological PropertiesDescriptors
Reference23900004
Compounds from ReferenceOther compounds from reference
Find Similar Compounds
                                   

Reported activity against other enzymesFGFR-1 | VEGFR-2 | PDGFRβ | Src | Abl | ALL
Pub Chem Link -
Drug Bank Link -
ChemSpider Link -
ChEMBL Link -
 
TOP