Epidermal Growth Factor Receptor Inhibitor Database
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| Activity against kinases | ||||||||||||||
| Molecule Id: EGIN0005039 | ||||||||||||||
| S.No. | Kinase | Mutant | IC50 | Ki | Kd | Enz. inhib. (%) | Inhib. Conc. | Cellular IC50 | Cell line | Growth Factor | ||||
| 1 | FGFR-1 | - | 63±25 nM | - | - | - | - | - | - | - | ||||
| 2 | VEGFR-2 | - | - | - | - | 30% | - | - | - | - | ||||
| 3 | PDGFRβ | - | - | - | - | 40% | - | - | - | - | ||||
| 4 | Src | - | 645±85 nM | - | - | - | - | - | - | - | ||||
| 5 | Abl | - | 56±16 nM | - | - | - | - | - | - | - | ||||