ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
TYMP	1890	9570975	Endometrial adenocarcinoma + Endometrial adenosquamous	-	-	-	-	42 (43 endometrial adenocarcinoma + 3 endometrial adenosquamous)	31 to 79	59	Shimane Medical University Hospital	IA (n=9); IB (n=16); IC (n=8); IIA (n=1); IIB (n=6); IIIC (n=6)	1 (n=32); 2 (n=11); 3 (n=3)	[1] TP may play an important role in angiogenesis and may be involved in the tumorigenesis of endometrial cancer. [2] Of the 46 tumors; 19 (41%) were TP-positive. The microvessel count was significantly higher in TP-positive tumors than in TP-negative tumors (P = 0.01).	Immunohistochemical expression of thymidine phosphorylase in human endometrial cancer.	Gynecologic Oncology	68(3):247-52	1998
TYMP	1890	9751263	-	-	-	-	-	59	33 to 74	-	Department of Obsterics and Gynecology; Gifu University School of Medicine	-	-	[1] The active availability of PD-ECGF might contribute to the acceleration of angiogenic activity in the early process of invasion of well-differentiated uterine endometrial cancers. [2] The levels of PD-ECGF were significantly higher in uterine endometrial cancers of well-differentiated grade (G1) with invasion to < or =1/2 myometrium (B) and of stage 1 than in those of moderately and poorly differentiated grades (G2 and G3; respectively) limited to endometrium (A) and with invasion to >1/2 myometrium (C) and of stages II and III/IV and in normal uterine endometria.	Expression of platelet-derived endothelial cell growth factor (PD-ECGF) and its mRNA in uterine endometrial cancers.	Cancer Letters	130(1-2):115-20	1998