ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
STK11	6794	18245476	Endometrioid adenocarcinoma	-	-	-	-	-	-	-	-	-	-	[1] In human endometrial cancers; Lkb1 expression was inversely correlated with tumor grade and stage; arguing that Lkb1 inactivation or down-regulation also contributes to endometrial cancer progression in women. This study shows that Lkb1 plays an important role in the malignant transformation of endometrium and that Lkb1 loss promotes a highly invasive phenotype.	Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.	Cancer Research	68(3):759-66	2008