ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
KLK10	5655	16647913	Uterine serous papillary carcinomas	Up regulation/ Over expression/High expression	Biomarker	-	-	11 USPCs; 2 Ecs; 5 OSPC	-	-	Gynecologic Oncology Division and Pathology Department; University of Arkansas for Medical Science	-	-	[1] Kallikrein 10 is highly expressed in uterine serous papillary carcinoma; and it is released in the plasma and serum of uterine serous papillary carcinoma patients. [2] Kallikrein 10 gene expression levels were significantly higher in uterine serous papillary carcinoma when compared with normal endometrial cell biopsies (mean copy number by real time polymerase chain reaction = 743 versus 1.4; uterine serous papillary carcinoma versus endometrioid carcinoma: P < .02). [3] Serum and plasma kallikrein 10 values in uterine serous papillary carcinoma patients (1.2 +/- 0.1) were significantly higher than those in the non-cancer group (P = .002); benign group (P = .002); and endometrioid carcinoma patients (P = .005).	Overexpression of kallikrein 10 (hK10) in uterine serous papillary carcinomas.	American Journal of Obstetrics and Gynecology	194(5):1296-302	2006