ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
FOLH1	2346	18349274	-	Down regulation/ Down expression	Prognostic Marker	-	-	-	30 to 87	66	Roswell Park Cancer Institute; Newyork	I (n=83); II (n=21); III (n=17); IV (n=9)	1 (n=51); 2 (n=46); 3 (n=33)	[1] PSMA is underexpressed in advanced stage EAC; [2] loss ofPSMA expression can be considered as a prognosticmarker in patients with EAC; and [3] loss of PSMAexpression in a subset of EAC cases couldbe due toepigenetic silencing. [4] There is an association between PSMA methylationandtumor size (P = 0.025). [5] High PSMA mRNA levels was significantly associated withFIGO stage I disease (P = 0.046).	Prostate-specific membrane antigen expression is a potential prognostic marker in endometrial adenocarcinoma.	Cancer epidemiology; biomarkers & prevention	17(3):571-7	2008