ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
EFNB2	1948	17108150	-	Up regulation/ Over expression/High expression	-	Prognostic Marker	-	-	35 to 79	-	Department of Obstetrics and Gynecology; Gifu University School of Medicine; Japan	I (n=25); II (n=21); III (n=22)	1 (n=24); 2 (n=22); 3 (n=22)	[1] EphrinB2 is overexpressed during the tumor advancement as dedifferentiation and myometrial invasion. Therefore; ephrinB2 might work on tumor advancement and may be recognized as a novel prognostic indicator for uterine endometrial cancers. [2] EphrinB2 histoscores are highly correlated with ephrinB2 mRNA levels; (r = 0.864; P < 0.01). Both the histoscores and mRNA levels of ephrinB2 significantly increased with clinical stages (I < II < III; P < 0.01); dedifferentiation (G(1) < G(2) < G(3); P < 0.01) and myometrial invasion (A < B < C; P < 0.01) in uterine endometrial cancers.	Overexpression of ephrinB2 and EphB4 in tumor advancement of uterine endometrial cancers.	Annals of Oncology	18(3):485-90	2007