ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
CEACAM1	634	15930340	-	Differentially expressed		-	-	119 (66 endometrioid; 24 papillary serous; 29 mixed mullerian tumors)	-	-	Duke University Medical Centre; North Carolina	-	-	[1] The microarray study shows that this gene is differently expressed in endometrioid carcinoma profile; reflecting expression value 2.633 and 4.250 on both the endometrioid versus papillary serous carcionma and endometrioid versus mixed mullerian tumor respectively.	Microarray analysis of endometrial carcinomas and mixed mullerian tumors reveals distinct gene expression profiles associated with different histologic types of uterine cancer	Clinical Cancer Research	11(11):4056-66	2005
CEACAM1	634	9626043	-	-	-	-	24 (10 proliferative+ 14 secretory)	47 (39 endometroid+8 serous papillary)		-	-	-	1 (n=15); 2 (n=12); 3 (n=12)	"[1] Strong CD66a expression was observed in glandular and luminal epithelial cells of the normal endometrium with a consistent localization at the apical poles of these cells throughout the cycle. [2] The apical expression pattern of the normal epithelium was changed to a membranous all-around pattern in 55% of the tumors	mostly in solid areas. This change correlated with malignancy grade and could be observed in 3 of 15 G1 tumors	4 of 12 G2 tumors	11 of 12 G3 tumors	0