REFERENCES


Gene Name Gene ID Pubmed ID Classification Mechanism Marker Type Normal Cases Disease Cases Age Mean Age Place FIGO Grade Remark Title Journal Volume Year
BRAF673 16144912-  Mutation  -  -  20 (10 proliferative+ 10 secretory)  97 (78 endometroid adenocarcinoma+ 12 serous papillary + 6 clear cell carcinomas)  30 to 76  -  Shinshu University Hospital  I (n=52); II (n=10); III (n=28); IV (n=7)  1 (n=36); 2 (n=19); 3 (n=23)   20 (21%) and 1 (11%) had BRAF mutations   most of them at previously unreported sites. Twenty samples of normal endometrium and 21 samples of normal endometrium obtained from sites adjacent to neoplastic lesions had no BRAF mutations. There was no apparent difference in the prevalence of BRAF mutation among stages   histologic subtypes  0