ECDB-Endometrial cancer gene database

REFERENCES

Gene Name	Gene ID	Pubmed ID	Classification	Mechanism	Marker	Type	Normal Cases	Disease Cases	Age	Mean Age	Place	FIGO	Grade	Remark	Title	Journal	Volume	Year
BCL2L1	598	20178603	-	Up regulation/ Over expression/High expression	-	-	10 (6 proliferative+ 4 secretory)	50 (6 simple hyperplasia + 12 atypical hyperplasia+ 32 endometrial carcinoma)	34 to 70 (patient); 37 to 59 (control)	52 (patient); 48 (control)	Department of Obstetrics and Gynecology; Hospital of China Medical University	I (n=22); II (n=4); III (n=6)	1 (n=14); 2 (n=12); 3 (n=6)	[1] The abnormal expressions of Bcl-xs and Bcl-xl were one of the molecular mechanisms for the pathogenesis of endometrial carcinoma; and altered ratio between these two might involve in the onset of endometrial carcinoma. [2] Bcl-xl expression in endometrial carcinoma tissue was significantly higher than the normal endometrial tissue (P = 0.00); which was correlated with the pathological grading of endometrial carcinoma (F = 5.33; P = 0.02).	Relevance of Bcl-x expression in different types of endometrial tissues	Journal of Experimental and Clinical Research	29:14	2010