Browse result page of DenvInD
The total number entries retrieved from this search are 365
| DenvInD_ID | IUPAC Name | CID | SID | AID | SMILES | IC50 | Ki | EC50 | CC50 | PMID | Protein Name |
|---|---|---|---|---|---|---|---|---|---|---|---|
| DenvInD_151 | 2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[2-[[(2S)-2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]propanoyl]amino]acetyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]acetic acid | 71455120 | 163324161 | 697535 | CC(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NCC(=O)O)NC(=O)C(CS)N | NA | 42 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_152 | (4R,7S,10S,19R)-19-amino-10-(4-aminobutyl)-7-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxylic acid | 71462306 | 163338035 | 697535 | CC(C)CC1C(=O)NC(CSSCC(C(=O)NCC(=O)NCC(=O)NC(C(=O)N1)CCCCN)N)C(=O)O | NA | 15.1 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_153 | (4R,7S,10S,13R,19R)-19-amino-13-(4-aminobutyl)-7,10-bis[3-(diaminomethylideneamino)propyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxylic acid | 71460600 | 164130501 | 697535 | C1C(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSS1)C(=O)O)CCCN=C(N)N)CCCN=C(N)N)CCCCN)N | NA | 3.5 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_154 | (4R,7S,10S,13S,19R)-19-amino-10-(4-aminobutyl)-7-[3-(diaminomethylideneamino)propyl]-13-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxylic acid | 71455121 | 164136102 | 697535 | C1C(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSS1)C(=O)O)CCCN=C(N)N)CCCCN)CC2=CC=C(C=C2)O)N | NA | 5 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_155 | (4R,7S,10S,13S,16R,22R)-22-amino-10,16-bis(4-aminobutyl)-13-[3-(diaminomethylideneamino)propyl]-7-(2-methylpropyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxylic acid | 71460599 | 164138989 | 697535 | CC(C)CC1C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CCCN=C(N)N)CCCCN)N)C(=O)O | NA | 2.5 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_156 | (4R,7S,10S,13S,16R,22R)-22-amino-10,16-bis(4-aminobutyl)-13-[3-(diaminomethylideneamino)propyl]-7-(hydroxymethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxylic acid | 71462305 | 164144540 | 697535 | C1C(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSS1)C(=O)O)CO)CCCCN)CCCN=C(N)N)CCCCN)N | NA | 1.4 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_157 | (4R,10S,13S,19R)-19-amino-10-(4-aminobutyl)-13-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxylic acid | 71451581 | 164144541 | 697535 | C1C(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(CSS1)C(=O)O)CCCCN)CC2=CC=C(C=C2)O)N | NA | 12 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_158 | 2-[3-[(2S,5S,8S,14S,20R)-5,20-bis(4-aminobutyl)-8-(hydroxymethyl)-14-methyl-3,6,9,12,15,18,21-heptaoxo-1,4,7,10,13,16,19-heptazacyclohenicos-2-yl]propyl]guanidine | 71458789 | 164147320 | 697535 | CC1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CO)CCCCN)CCCN=C(N)N)CCCCN | NA | 11.3 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_159 | 2-[3-[(2S,5S,8S,14S,17S,23R)-5,23-bis(4-aminobutyl)-8-(hydroxymethyl)-17-methyl-3,6,9,12,15,18,21,24-octaoxo-14-(sulfanylmethyl)-1,4,7,10,13,16,19,22-octazacyclotetracos-2-yl]propyl]guanidine | 71458788 | 174494477 | 697535 | CC1C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)N1)CS)CO)CCCCN)CCCN=C(N)N)CCCCN | NA | 2.2 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_160 | (4R,7S,10S,13R,19R)-19-amino-10-(4-aminobutyl)-13-[(4-hydroxyphenyl)methyl]-7-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxylic acid | 71453420 | 174510009 | 697535 | CC(C)CC1C(=O)NC(CSSCC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CC=C(C=C2)O)N)C(=O)O | NA | 12.5 | NA | NA | 22780881 | NS3 Protease |
| DenvInD_161 | N-[(2S)-1-[[(2S)-6-amino-1-[[(1R)-2-amino-2-oxo-1-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]ethyl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1,3-thiazole-2-carboxamide | 127039816 | 336889294 | 1265611 | C1=CC(=CC=C1COC2=CC=C(C=C2)C(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C3=NC=CS3)C(F)(F)F | NA | NA | 3.4 μM | NA | 26562070 | NS3 Protease |
| DenvInD_162 | N-[(2S)-1-[[(2S)-6-amino-1-[[(1R)-2-amino-2-oxo-1-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]ethyl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1,3-thiazole-2-carboxamide | 127039816 | 336889294 | 1265611 | C1=CC(=CC=C1COC2=CC=C(C=C2)C(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C3=NC=CS3)C(F)(F)F | NA | NA | 0.012 μM | NA | 26562070 | NS3 Protease |
| DenvInD_163 | N-[(2S)-1-[[(2S)-6-amino-1-[[(1R)-2-amino-1-[4-[(3-methoxyphenyl)methoxy]phenyl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-5-thiophen-2-ylthiophene-2-carboxamide | 127040513 | 336890152 | 1265611 | COC1=CC=CC(=C1)COC2=CC=C(C=C2)C(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C3=CC=C(S3)C4=CC=CS4 | 0.176 | NA | NA | NA | 26562070 | NS3 Protease |
| DenvInD_164 | 3-[(1R,7R,10S,13S,16S,19S,25S,28S,31R,34S,37S,40S,46S,52S,55S,58R,64S,67S,70S,73S,76S,79S,85R,90S,93S)-90-amino-10,13,37,40,76,79-hexakis(3-carbamimidamidopropyl)-67-(2-carboxyethyl)-34,93-bis[(1R)-1-hydroxyethyl]-16,64,73-tris(hydroxymethyl)-19-(1H-indol-3-ylmethyl)-46-(2-methylpropyl)-2,5,8,11,14,17,20,26,29,32,35,38,41,44,47,53,56,59,62,65,68,71,74,77,80,83,86,88,91,94-triacontaoxo-28,55-di(propan-2-yl)-7,31,58,85-tetrakis(sulfanylmethyl)-3,6,9,12,15,18,21,27,30,33,36,39,42,45,48,54,57,60,63,66,69,72,75,78,81,84,87,92,95-nonacosazatetracyclo[93.3.0.021,25.048,52]octanonacontan-70-yl]propanoic acid | 46231130 | 103726334 | 460481 | CC(C)CC1C(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(=O)CC(C(=O)NC(C(=O)N3CCCC3C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N4CCCC4C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CCCNC(=N)N)CCCNC(=N)N)C(C)O)CS)C(C)C)CC5=CNC6=CC=CC=C65)CO)CCCNC(=N)N)CCCNC(=N)N)CS)C(C)O)N)CS)CCCNC(=N)N)CCCNC(=N)N)CO)CCC(=O)O)CCC(=O)O)CO)CS)C(C)C | NA | NA | NA | NA | 20042339 | NS3 Protease |
| DenvInD_165 | 3-[(1R,4S,7S,13S,19S,22S,25S,28R,31S,34S,40S,43S,46S,49S,52R,58S,64S,67S,72R,78S,81S,84S,87S,90S,93S)-67-amino-19,22,46,49,78,81-hexakis(3-carbamimidamidopropyl)-90-(2-carboxyethyl)-25,64-bis[(1R)-1-hydroxyethyl]-43,84,93-tris(hydroxymethyl)-40-(1H-indol-3-ylmethyl)-13-(2-methylpropyl)-3,6,12,15,18,21,24,27,30,33,39,42,45,48,51,54,57,63,66,69,71,74,77,80,83,86,89,92,95,98-triacontaoxo-4,31-di(propan-2-yl)-a,1a,4a,5a-tetrathia-2,5,11,14,17,20,23,26,29,32,38,41,44,47,50,53,56,62,65,70,73,76,79,82,85,88,91,94,97-nonacosazahexacyclo[70.26.4.428,52.07,11.034,38.058,62]hexahectan-87-yl]propanoic acid | 46231132 | 103726336 | 460481 | CC(C)CC1C(=O)N2CCCC2C(=O)NC(C(=O)NC3CSSCC(C(=O)NC(=O)CC(C(=O)NC(C(=O)N4CCCC4C(=O)NCC(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CCCNC(=N)N)CCCNC(=N)N)C(C)O)NC(=O)C(NC(=O)C6CCCN6C(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CCCNC(=N)N)CCCNC(=N)N)CO)CC7=CNC8=CC=CC=C87)C(C)C)C(C)O)N)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CO)CCC(=O)O)CCC(=O)O)CO)CCCNC(=N)N)CCCNC(=N)N)C(C)C | NA | 1.39 | NA | NA | 20042339 | NS3 Protease |
| DenvInD_166 | 3-[(1R,4S,7S,13S,19S,22S,25S,28R,31S,34S,40S,43S,46S,49S,52R,58S,64S,67S,72R,78S,81S,84S,87S,90S,93S)-67-amino-19,22,46,49,78,81-hexakis(3-carbamimidamidopropyl)-90-(2-carboxyethyl)-25,64-bis[(1R)-1-hydroxyethyl]-43,84,93-tris(hydroxymethyl)-40-(1H-indol-3-ylmethyl)-13-(2-methylpropyl)-3,6,12,15,18,21,24,27,30,33,39,42,45,48,51,54,57,63,66,69,71,74,77,80,83,86,89,92,95,98-triacontaoxo-4,31-di(propan-2-yl)-a,1a,4a,5a-tetrathia-2,5,11,14,17,20,23,26,29,32,38,41,44,47,50,53,56,62,65,70,73,76,79,82,85,88,91,94,97-nonacosazahexacyclo[70.26.4.428,52.07,11.034,38.058,62]hexahectan-87-yl]propanoic acid | 46231132 | 103726336 | 460481 | CC(C)CC1C(=O)N2CCCC2C(=O)NC(C(=O)NC3CSSCC(C(=O)NC(=O)CC(C(=O)NC(C(=O)N4CCCC4C(=O)NCC(=O)NC5CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CCCNC(=N)N)CCCNC(=N)N)C(C)O)NC(=O)C(NC(=O)C6CCCN6C(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC5=O)CCCNC(=N)N)CCCNC(=N)N)CO)CC7=CNC8=CC=CC=C87)C(C)C)C(C)O)N)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CO)CCC(=O)O)CCC(=O)O)CO)CCCNC(=N)N)CCCNC(=N)N)C(C)C | NA | 1.39 | NA | NA | 20042339 | NS3 Protease |
| DenvInD_167 | 3-[(1R,4S,7S,13S,16S,19S,22S,25R,31S,37S,40S,45R,51S,54S,57S,60S,63S,66S,72R,75S,78S,84S,90S,93S,96S)-40-amino-19,22,51,54,90,93-hexakis(3-carbamimidamidopropyl)-63-(2-carboxyethyl)-37,96-bis[(1R)-1-hydroxyethyl]-16,57,66-tris(hydroxymethyl)-13-(1H-indol-3-ylmethyl)-84-(2-methylpropyl)-3,6,12,15,18,21,24,27,30,36,39,42,44,47,50,53,56,59,62,65,68,71,74,77,83,86,89,92,95,98-triacontaoxo-4,75-di(propan-2-yl)-a,1a,4a,5a-tetrathia-2,5,11,14,17,20,23,26,29,35,38,43,46,49,52,55,58,61,64,67,70,73,76,82,85,88,91,94,97-nonacosazahexacyclo[70.26.4.425,45.07,11.031,35.078,82]hexahectan-60-yl]propanoic acid | 46231133 | 103726337 | 460481 | CC(C)CC1C(=O)N2CCCC2C(=O)NC(C(=O)NC3CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CCCNC(=N)N)CCCNC(=N)N)C(C)O)NC(=O)C(NC(=O)C4CCCN4C(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C5CSSCC(C(=O)NC(=O)CC(C(=O)NC(C(=O)N6CCCC6C(=O)NCC(=O)N5)C(C)O)N)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CO)CCC(=O)O)CCC(=O)O)CO)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CO)CC7=CNC8=CC=CC=C87)C(C)C)C(C)C | 9.3 | NA | NA | NA | 20042339 | NS3 Protease |
| DenvInD_168 | 3-[(1R,4S,7S,13S,16S,19S,22S,25R,31S,37S,40S,45R,51S,54S,57S,60S,63S,66S,72R,75S,78S,84S,90S,93S,96S)-40-amino-19,22,51,54,90,93-hexakis(3-carbamimidamidopropyl)-63-(2-carboxyethyl)-37,96-bis[(1R)-1-hydroxyethyl]-16,57,66-tris(hydroxymethyl)-13-(1H-indol-3-ylmethyl)-84-(2-methylpropyl)-3,6,12,15,18,21,24,27,30,36,39,42,44,47,50,53,56,59,62,65,68,71,74,77,83,86,89,92,95,98-triacontaoxo-4,75-di(propan-2-yl)-a,1a,4a,5a-tetrathia-2,5,11,14,17,20,23,26,29,35,38,43,46,49,52,55,58,61,64,67,70,73,76,82,85,88,91,94,97-nonacosazahexacyclo[70.26.4.425,45.07,11.031,35.078,82]hexahectan-60-yl]propanoic acid | 46231133 | 103726337 | 460481 | CC(C)CC1C(=O)N2CCCC2C(=O)NC(C(=O)NC3CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1)CCCNC(=N)N)CCCNC(=N)N)C(C)O)NC(=O)C(NC(=O)C4CCCN4C(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C5CSSCC(C(=O)NC(=O)CC(C(=O)NC(C(=O)N6CCCC6C(=O)NCC(=O)N5)C(C)O)N)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CO)CCC(=O)O)CCC(=O)O)CO)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CO)CC7=CNC8=CC=CC=C87)C(C)C)C(C)C | NA | 3.03 | NA | NA | 20042339 | NS3 Protease |
| DenvInD_169 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-cyclohexyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72710920 | 174514694 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)C3CCCCC3 | 6.1 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_170 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-cyclohexyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72710921 | 174525049 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)C3CCCCC3 | 3.4 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_171 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-butyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72714175 | 174525048 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CCCC | 3.5 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_172 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-chlorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712240 | 174525046 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=C(C=C3)Cl | 3.2 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_173 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]thiophene-2-carboxamide | 73357148 | 174525045 | 776943 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=CS1 | 14.1 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_174 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-butyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72713955 | 174525041 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CCCC | 6.2 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_175 | methyl 2-[(5Z)-5-[[4-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoate | 72710923 | 174525026 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)C(CCCC)C(=O)OC | 11.6 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_176 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-methylphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72711812 | 174525023 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CC3=CC=C(C=C3)C | 7.5 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_177 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712029 | 174519754 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=C(C=C3)F | 2.9 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_178 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712027 | 174519753 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=C(C=C3)OC | 3.3 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_179 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(E)-3-amino-3-oxoprop-1-enyl]benzamide | 73355607 | 174519752 | 776943 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=CC(=O)N | 6.4 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_180 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(E)-2-cyano-3-(cyclopropylamino)-3-oxoprop-1-enyl]benzamide | 73354076 | 174514709 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C(C#N)C(=O)NC2CC2 | 5.3 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_181 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72711810 | 174488991 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CC3=CC=CC=C3 | 10.9 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_182 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72711811 | 174514691 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=CC=C3 | 2.9 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_183 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712241 | 174509533 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CCC3=CC=CC=C3 | 7.7 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_184 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-cyclohexyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72710920 | 174514694 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)C3CCCCC3 | 6.1 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_185 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-cyclohexyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72710921 | 174525049 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)C3CCCCC3 | 3.4 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_186 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-butyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72714175 | 174525048 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CCCC | 3.5 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_187 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-chlorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712240 | 174525046 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=C(C=C3)Cl | 3.2 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_188 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]thiophene-2-carboxamide | 73357148 | 174525045 | 776943 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=CS1 | 14.1 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_189 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-butyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72713955 | 174525041 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CCCC | 6.2 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_190 | methyl 2-[(5Z)-5-[[4-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoate | 72710923 | 174525026 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)C(CCCC)C(=O)OC | 11.6 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_191 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-methylphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72711812 | 174525023 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CC3=CC=C(C=C3)C | 7.5 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_192 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712029 | 174519754 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=C(C=C3)F | 2.9 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_193 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712027 | 174519753 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=C(C=C3)OC | 3.3 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_194 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(E)-3-amino-3-oxoprop-1-enyl]benzamide | 73355607 | 174519752 | 776943 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=CC(=O)N | 6.4 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_195 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(E)-2-cyano-3-(cyclopropylamino)-3-oxoprop-1-enyl]benzamide | 73354076 | 174514709 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C(C#N)C(=O)NC2CC2 | 5.3 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_196 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72711810 | 174488991 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CC3=CC=CC=C3 | 10.9 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_197 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-(3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide | 72711811 | 174514691 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CC3=CC=CC=C3 | 2.9 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_198 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712241 | 174509533 | 776941 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CCC3=CC=CC=C3 | 7.7 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_199 | 2-[(5Z)-5-[[4-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]phenyl]methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl acetate | 72711375 | 174504445 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=O)S2)CCOC(=O)C | 4.8 | NA | NA | NA | 24083834 | NS3 Protease |
| DenvInD_200 | N-[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-[(Z)-[3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]benzamide | 72712026 | 174504419 | 776942 | CCCCC(C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)CC3=CC=C(C=C3)OC | 7.9 | NA | NA | NA | 24083834 | NS3 Protease |