| Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
| TP53 | 10534770 | - | Department of Pathology, Leiden University Medical Centre | TP53 is deregulated by the HPV-encoded E6 protein. Binding of E6 to TP53 results in TP53 degradation through the ubiquitin proteolysis pathway. |
| TP53 | 19423538 | Polymorphism | Guanacaste cohort, Costa Rica | Three common SNPs (rs12951053, rs1042522 and rs1642785) in TP53 are associated with risk of CIN3+ or HPV persistence with Ptrends of 0.05,0.002 and 0.04 respectively. |
| TP53 | 18813814 | Upregulation | Department of Obsterics and Gynaecology of the University Hospital of Heraklion, Crete | This gene is found to be upregulated 80%,69% and 64% in tumors,HSIL and LSIL cases. |
| TP53 | 12657131 | - | - | p53 is frequenlty expressed (75%, 21 of 28 cases) in small cell carcinomas of the cervix. |
| TP53 | 15073118 | Overexpression | Umea University Hospital, Sweden | p53 expression is increased gradually with progression of lesions. Its expression is high in CIN (63%; P<0.01) and in SCC 100%;P<0.05) |
| TP53 | 10999751 | | - | p53 expression is detected in 28.6% in noninvasive squamous cell carcinoma and 69.6% of invasive squamous cell carcinoma (P<0.02). |
| TP53 | 20200430 | - | - | The arginine peptide of TP53 codon 72 was overestimated in Caucasian families (p=0.043) and the significane of this finding was enhanced in a subgroup of women infected with HPV-16 and/or HPV 18 related HPVs (p=0.026). |