| Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
| MGMT | 11297252 | Methylation | Parkland Health and Hospital System, Dallas, Texas. | MGMT is methylated at relatively high frquencies in high grade CIN and in invasie carcinoma (26-29%), although methylation is lower in the nondysplasia/low grade CIN group. Also methylation of MGMT, which modulates response to cytotoxic agents, may play an important role in cervical cancer. |
| MGMT | 17971771 | Methylation | VU University Medical Center in Amerstdam | MGMT is the most frequently methylated in both tumour histotypes, that is in 92% in all carcinomas. |
| MGMT | 14760078 | Methylation | Department of Obsterics and Gynecology, Innsbruck University Hospital. | Aberrant methylation of CpG island within the promoter regions. |
| MGMT | 19513524 | Methylation | Colposcopy Unit of University Hospital of Larissa; Greece. | MGMT promoter methylation is found in 13.3% of normal cases, 28.2% of premalignant cases and 72.5% of cancer cases. |
| MGMT | 11448914 | Methylation | - | Aberrant methylation of CpG island within the promoter regions. |
| MGMT | 19836067 | Methylation | Chonnam National University Hwasun Hospital | The trend of methylation of this gene is increasing with increasing severity of cervical squamous lesions (p<0.001). |
| MGMT | 15589597 | Methylation | Department of Obstertics and Gynecology, Seoul national University Hospital. | Frequency of methylation of this gene is found to be 19.5%. |
| MGMT | 15785933 | Methylation | Department of pathology, Anam Hospital of Korea University | None of 20 non-neoplastic cervices showed p16 INK4A and MGMT gene hypermethylation, whereas at least one of these genes was hypermethylated with 50.0% (5/10) of CIN I, 65.0% (13/20) of CIN II-III, 70.2% (33/47) of SCC and 85.0% (17/20) of adenocarcinoma |
| MGMT | 16928264 | Methylation | - | Incidence of hypermethylation for DAPK, MGMT, p16 and PTEN in cervical cancer was 56.7%, 25.2%, 16.5% and 15.7% respectively |
| MGMT | 15099958 | Methylation | Queen Mary Hospital, Hong Kong. | Promotor CpG island methylation of DAPK, p16, and MGMT was detectable, respectively, in 60%, 28.2%, and 18.8% of cases of cervical tumor DNA, and in 40%, 10%, and 7.5% of cases of patients' plasma DNA |
| MGMT | 15713962 | Methylation | - | hypermethylation rates were twice as high among samples from women with confirmed ICC as the rates among samples from women with CIN-1 or less |