Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
MDM2 | 17306351 | Overexpression | Clinic of Obstetrics and Gynaecology at the Medical University of Vienna, Austria. | MDM2 protoncogene showed a 4.62 fold higher increase in malignant cervical squamous cells   |
MDM2 | 18813814 | Upregulation | Department of Obsterics and Gynaecology of the University Hospital of Heraklion, Crete | This gene is found to be upregulated 88% and 73% in HSIL and LSIL cases.   |
MDM2 | 20200430 | - | - | The combination of high levels of MDM2 with the G-allele of SNP309 can severley weaken the p53 tumor suppressor pathway resulting in higher mutation rate, less efficient DNA repair and reduced apoptosis.   |