| Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
| CDH1 | 12773202 | Methylation | Instituto Nacional de Cancerologia, Colombia and Department of Obstetrics and Gynecology of Friedrich Schiller University, Jena, Germany | The frequency of methylation of CDH1 gene promoter is 51.1%. |
| CDH1 | 17894941 | Methylation | Washington University School of Medicine | Hypermethylation results have been noted for CDH1. Thus it can be used as a potential markers for cervical neoplasia.Methylation of CDH1 was found in 89% of cancers and 26% of CIN3 cytology specimens. |
| CDH1 | 16331610 | Methylation | Gynecologic Oncology Division of Seoul National University Hospital | Methylation of this gene is more frequently in AC than SCC (80.6%,P=0.001) |
| CDH1 | 14760078 | Methylation | Department of Obsterics and Gynecology, Innsbruck University Hospital. | Aberrant methylation of CpG island within the promoter regions. |
| CDH1 | 12657131 | - | - | Loss of E-cadherin expression correlated with the loss of tumor adhesion and increased tumor aggressivness in carcinoma. |
| CDH1 | 11448914 | Methylation | Samsung Cheil Hospital, Seoul, Korea | Aberrant methylation of CpG island within the promoter regions in asscoiation with the loss of protein expression in cancer cells. |
| CDH1 | 12702579 | Methylation | Anatomical Pathology Department of the City of Hope National Medical Center. | Aberrant methylation of CpG island within the promoter regions has been observed in the 25-50% of the tumors. |
| CDH1 | 12751384 | Methylation | Department of Obsterics and Gynecology, University of HongKong | Methylation of E-cadherin is significantly correlated with increased DNMT1. |
| CDH1 | 17009983 | Methylation | Central Hospital of Gynecology and Obsterics, Tianjin, China | Methylation of E-cadherin gene was detected inn 39.74% of plasam samples of cervical patients. Thus methylation of E-daherin gene in plasma samples will become a sensitive marker for the detection of cervical cancers. And methylation of this gene influences the genesis and progression of cervical cancer. |
| CDH1 | 12751384 | Methylation | Department of Obsterics and Gynecology, University of HOngKong | E-cadherin methylation is significantly correlated with the increased DNMT1. |
| CDH1 | 16803511 | Methylation | Busan Paik Hospital, Inje University, Busan, South Korea. | The frequencies of promoter methylation of p16, DAPK, CDH1, and TIMP-3 in cervical cancer were 57%, 44.9%, 52.6%, and 9%, respectively |
| CDH1 | 19755648 | Methylation | Coloscopy Clinic, Jessop Wing or the Oncology Department of the Royal hallamshire Hospital, Sheffield. | Tumor suppressor gene CDH1 exhibited a significantly increased frequency of promoter methylation with progressively more severe cervical neoplasia (P < 0.05). HIC1 gene is reported to be a potential biomarker of cervical neoplasia |