REFERENCES


Gene Name Pubmed ID Classification Sample Location Remark
CCNA1 19843677MethylationUniversity Medical Center, Groningen.Methylation of CCNA1 in cervical scrappings is strongly associated with CIN II or higher grade lesions. This marker might be used for direct referral to gynecologists for patients with a methylation-positive scrapping.  
CCNA1 20208141MethylationPathology Archives of the University Medical Center Groningen (UMCG).Methylation of CCNA1 increases during cervical carcinogenesis and thus is reported as one of the best markers to distinguish normal/LSIL from HSIL/cancer lesions.  
CCNA1 16524460Methylation-The frquency of CCNA1 methylation is high and specific to invasive cancer so is a good candidate for early detection. CCNA1 promoter methylation in HPV-associated squamous cell CC is unusually common.