Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
CCNA1 | 19843677 | Methylation | University Medical Center, Groningen. | Methylation of CCNA1 in cervical scrappings is strongly associated with CIN II or higher grade lesions. This marker might be used for direct referral to gynecologists for patients with a methylation-positive scrapping.   |
CCNA1 | 20208141 | Methylation | Pathology Archives of the University Medical Center Groningen (UMCG). | Methylation of CCNA1 increases during cervical carcinogenesis and thus is reported as one of the best markers to distinguish normal/LSIL from HSIL/cancer lesions.   |
CCNA1 | 16524460 | Methylation | - | The frquency of CCNA1 methylation is high and specific to invasive cancer so is a good candidate for early detection. CCNA1 promoter methylation in HPV-associated squamous cell CC is unusually common.   |