About AHTPDB
It is a manually curated database of experimentally validated Antihypertensive peptides (AHTPs). It contains around 6000 entries of about 1700 unique peptides. Each entry provides comprehensive information about a peptide that includes its sequence, inhibitory concentration (IC50), log value of inhibitory concentration (pIC50) and toxicity. These peptides have been collected & complied from published literature and existing databases like ACEpepDB, BIOPEP and EROP-Moscow database.
Extended information has been provided in terms of external links as well as mapping of AHTPs on major databases like Swiss-Prot, IEDB and PDB.
| SALIENT FEATURES OF AHTPDB: |
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| SEARCH MODULE: | This module facilitates the users in Simple, Advanced seach apart from peptide based seach and SMILES search. |
| EXPLORE MODULE: | Users can explore AHTPDB on the basis of Sources, Length, IC50 and physicochemical properties. |
| FACILITY MODULE: | Basic sequence alignment in Jalview is incorporated besides Smith-Waterman search and peptide mapping tools. |
| PROPERTY MODULE: | Amino acid (AA) composition, AA frequency and Physicochemical Properties based search is available in this module. |
| STRUCTURE MODULE: | Secondary structure composition based search is available along with Tertiary structure alingment. |
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