Welcome to Entry Card of Peptide


Details of TopicalPdb ID 1646

PRIMARY INFORMATION
ID1646
PMID8321834
Year1992
SequenceMALWMRLLPLLALLAL
WGPDPAAAFVNQHLCGSH
LVEALYLVCGERGFFYTPKTR
REAEDLQVGQVELGGGPG
AGSLQPLALEGSLQKRG
IVEQCCTSICSLYQLENYCN
NameInsulin(porcine)
Length51
N-Terminal ModificationFree
C-Terminal ModificationFree
Linear/ CyclicLinear
ChiralityL
Chemical ModificationNone
Origin of PeptideSynthetic
Nature of Peptide/CargoNot mentioned
MechanismNot mentioned
Cargo Sequence/StructureNo cargo
Name of cargo
Not applicable
Assaypermeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from p – HEMA hydrogels was measured
EnhancerPH 3.6
Properties of enhancerNot mentioned
Concentration0.65mM
Incubation time36 hrs
Tissue permeability (value with units)0.654 (cm/sec) * 10 8
Tissue Sampleskin of hairless rat
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)
N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
NCC(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)
N[C@H](C(=O)N[C@H](C(=O)N[C@@H]
3C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N4[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N
[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H]
(C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C
(=O)NCC(=O)NCC(=O)NCC(=O)N5[C@H](C(=O)NCC(=O)N[C@H]
(C(=O)NCC(=O)N[C@H](