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Details of TopicalPdb ID 1120

PRIMARY INFORMATION
ID1120
PMID19486932
Year2009
SequencepGlu-HWSYwLRPG
NameTriptorelin
Length10
N-Terminal ModificationFree
C-Terminal ModificationAmidation
Linear/ CyclicLinear
ChiralityMix
Chemical ModificationpGlu= Pyroglutamic acid
Origin of PeptideSynthetic
Nature of Peptide/CargoLuteinizing hormone releasing hormone (LHRH) superagonist
MechanismNot mentioned
Cargo Sequence/StructureNone
Name of cargo
Not applicable
AssayFranz diffusion cell, HPLC
EnhancerContact area 2.0±0.1 cm2, triptorelin solution consists of 3 ml of 0.39 mg/ml peptide in pH 7.4 PBS
Properties of enhancerNot applicable
Concentrationsolution of 3 ml of 0.39 mg/ml peptide in pH 7.4 PBS
Incubation time24 hours
Tissue permeability (value with units)87.8±4.4% degraded
Tissue SampleInterior skin surface of dermatomed skin (DS) of porcine
Ex vivo/In vivo/In vitroin vitro
SECONDARY INFORMATION
STRUCTURE
Predicted Structure
SMILESN.A.